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Shortage Support

We all hear and talk about 'drug shortages' - but what do they really mean? A drug shortage is when a drug manufacturer is unable to supply a drug in order to meet the demands of consumers; meaning it is on back-order or completely out-of-stock. This can be caused by manufacturing delays, difficulty obtaining raw ingredients, discontinuation of the drug, or a sudden increase in the demand of a medication. During drug shortages, pharmaceutical compounding becomes an essential solution. Defined as the practice of preparing customized medications that are not otherwise commercially available, pharmaceutical compounding not only allows providers the opportunity to explore patient-tailored plans, but is also a critical safety net that allows providers to fill medication needs during product unavailability, like drug shortages.

To support compounding pharmacies and hospitals, Medisca closely monitors global shortages and proactively prepares formulas with step-by-step instructions on how to compound a given medication in need. As the bread and butter of compounding, formulas are one of the most sought after support during a drug shortage, and a priority for Medisca to assist on. On this web page is a consolidated list of formulas to support the preparation of medications that may currently or have recently been on shortage. All formulas are freely accessible. Prior to compounding any of these formulations, it is the pharmacist’s responsibility to ensure that they are aware of the current availability status of the commercial products and are compliant with all Provincial, State, Territory and Federal compounding regulations.

365
Shortages have been reported on a single day by the Society of Hospital Pharmacists Australia1
80+
Medisca Formulas to support current and former Australian Drug shortages, freely accessible below.


API(s) and Strength(s)Route of DeliveryDosage FormBaseFormula
Acetylcysteine 20% Inhalation Liquid Sterile Water for Injection, USP F 004 873
Acetylcysteine 200 mg per mL Oral Liquid Purified Water, USP F 007 673
Acyclovir 500 mg per 10 mL Injection Liquid Sterile Water for Injection, USP F 002 333
Alcohol Antiseptic 80% Topical Liquid Purified Water, USP F 008 676
Alendronate Sodium 91 mg per 75 mL Oral Liquid Purified Water, USP F 004 718
Alprostadil 40 mcg per mL Intrapenile Liquid Sterile Water for Injection, USP F 001 676
Aminophylline 25 mg per mL Intramuscular Liquid Sterile Water for Injection, USP F 000 740
Amitriptyline HCl 50 mg per 5 mL Oral Liquid Syrup (Simple), NF F 001 297
Amlodipine Besylate 1 mg per mL Oral Liquid Medisca Oral Mix F 006 038
Amoxicillin 125 mg per 5 mL, Potassium Clavulanate 31.25 mg per 5mL Oral Liquid Medisca Oral Mix F 009 779
Amoxicillin 250 mg per 5 mL Oral Liquid Medisca Oral Mix F 009 743
Amoxicillin 250 mg per 5 mL Oral Liquid Purified Water, USP F 000 338
Amoxicillin 250 mg per 5 mL, Potassium Clavulanate 62.5 mg per 5mL Oral Liquid ORA Blend® F 009 782
Amoxicillin 400 mg per 5 mL Oral Liquid Purified Water, USP F 003 572
Amoxicillin 400 mg per 5 mL G-Tube Liquid Purified Water, USP F 003 573
Amoxicillin 400 mg per 5 mL, Potassium Clavulanate 57 mg per 5mL Oral Liquid Medisca Oral Syrup + Medisca Oral Suspend F 009 783
Amoxicillin Trihydrate 1004.4 mg, Potassium Clavulanate 148.9 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 594
Anastrozole 1 mg Oral Capsules Lactose (Monohydrate), NF F 001 584
Arginine Hydrochloride 5 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 007 364
Atenolol 2 mg per mL Oral Liquid Medisca Oral Mix F 003 975
Atomoxetine Hydrochloride 5 mg per mL Oral Liquid Syrup (Simple), NF F 000 553
Atorvastatin 80 mg per 15 mL G-Tube Liquid Purified Water, USP F 003 423
Azithromycin 100 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 005 067
Azithromycin 200 mg per 5 mL Oral Liquid Medisca Oral Mix F 006 142
Azithromycin 200 mg per 5 mL Oral Liquid Medisca Oral Syrup + Medisca Oral Suspend F 004 074
Brimonidine Tartrate 0.05% Ophthalmic Liquid Sterile Water for Injection, USP F 007 350
Buprenorphine hydrochloride 1.62 mg per mL Transdermal Gel Medisca Pluornic Gel 20% (F 127) F 000 458
Bupropion Hydrochloride 150 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 555
Calcitriol 1 mcg per mL Injection Liquid Sterile Water for Injection, USP F 002 471
Carbidopa 25 mg per 5 mL_ Levodopa 250 mg per 5 mL Oral Liquid Purified Water, USP F 000 615
Carbidopa 25 mg, Levodopa 100 mg Oral Capsules Hypromellose (4000 CPS) Methocel E4M, USP + Cellulose (Microcrystalline), NF F 004 228
Cephalexin 250 mg per 5 mL Oral Liquid Purified Water, USP F 000 340
Clarithromycin 150 mg per 5 mL Oral Liquid Medisca Oral Mix F 006 143
Clindamycin Hydrochloride 40.72 mg Oral Capsules Lactose (Monohydrate), NF F 001 928
Desmopressin Acetate 50 mcg per mL Nasal Liquid Sterile Water for Injection, USP F 001 654
Diazepam 5 mg per mL Oral Liquid Syrup (Simple), NF F 000 473
Diltiazem Hydrochloride 10 mg per mL Oral Liquid Purified Water, USP F 006 148
Disulfiram 250 mg Oral Capsules Medisca CapsuBlend®-P F 000 272
Doxycycline hyclate 111 mg Oral Capsules Lactose (Monohydrate), NF F 000 526
Enalapril Maleate 10 mg per mL Oral Liquid Medisca Oral Mix F 006 149
Epinephrine 1 mg per mL Injection Liquid Sterile Water for Injection, USP F 002 207
Epinephrine 10 mcg per mL Intravenous Liquid Sodium Chloride 0.9% for Injection, USP (Sterile) F 004 337
Ethambutol Hydrochloride 300 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 806
Fentanyl 10 mcg per mL Epidural Liquid Sodium Chloride 0.9% for Injection, USP (Sterile, Preservative Free) F 003 731
Fentanyl 10 mcg per mL   Epidural Liquid Sodium Chloride 0.9% for Injection, USP (Sterile, Preservative Free) F 003 681
Fentanyl 5 mcg per mL Epidural Liquid Sodium Chloride 0.9% for Injection, USP (Sterile, Preservative Free) F 003 771
Fentanyl 50 mcg per mL Epidural Liquid Fentanyl 50 mcg per mL, Injection (Sterile, Preservative Free) ** F 004 217
Fentanyl Citrate 78.5 mcg Injection Liquid Sterile Water for Injection, USP F 004 979
Fluconazole 40 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 428
Fluoxetine Hydrochloride 22.4 mg per 5 mL Oral Liquid Syrup (Simple), NF F 003 753
Fluvoxamine Maleate 50 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 593
Furosemide 10 mg per mL Intramuscular, Intravenous Liquid Sterile Water for Injection, USP F 005 095
Gentamicin sulfate 169 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 000 942
Gentamicin sulfate 85 mg per mL Intramuscular, Intravenous Liquid Sterile Water for Injection, USP F 000 975
Heparin 5000 Units per mL Injection Liquid Sterile Water for Injection, USP F 001 515
Hydralazine Hydrochloride 10 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 004 313
Hydrochloride 30 mg Oral Capsules Lactose (Anhydrous), NF F 003 664 Oxycodone
Hydrocortisone 5 mg, 10 mg, 20 mg Oral Capsules Lactose (Monohydrate), NF F 002 000
Hydrocortisone 90 mg Rectal Suppositories  Medisca SPG Supposi-Base™ F 008 455
Hydroxychloroquine Sulfate 200 mg Oral Capsules Medisca CapsuBlend®-S F 008 628
Imipramine Hydrochloride 1 mg per mL   Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 126
Ipratropium Bromide 0.02% Inhalation Liquid Sterile Water for Injection, USP F 000 333
Ketamine HCl 11.5 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 007 516
Ketorolac Tromethamine 30 mg per mL Injection Liquid Sterile Water for Injection, USP F 003 032
Labetalol Hydrochloride 40 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 131
Lansoprazole 30 mg per 5 mL Oral Liquid Purified Water, USP + Syrup (Simple), NF F 000 302
Leucovorin 10 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 004 784
Lidocaine HCl 5% Oral Gel Medisca NovaFilm™ Gel Base F 008 448
Lisinopril 20 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 637
Losartan Potassium 6.25 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 332
Medroxyprogesterone Acetate 10 mg Oral Capsules Medisca CapsuBlend®-P F 004 871
Medroxyprogesterone Acetate 150 mg per mL Intramuscular Liquid Sterile Water for Injection, USP F 001 105
Metformin Hydrochloride 250 mg Oral Capsules Medisca CapsuBlend®-H F 004 814
Methotrexate 25 mg per mL Intramuscular Liquid Sterile Water for Injection, USP F 004 923
Methylprednisolone 4 mg per 5 mL Oral Liquid Medisca Oral Mix F 006 157
Methylprednisolone Acetate 80 mg per mL Intramuscular Liquid Sterile Water for Injection, USP F 004 811
Metoprolol Tartrate 1 mg per mL Subcutaneous Liquid Sterile Water for Injection, USP F 004 902
Metoprolol Tartrate 3 mg per 0.5 mL Oral Liquid Medisca Oral Mix F 006 150
Midazolam 1 mg per mL Epidural Liquid Sodium Chloride 0.9% for Injection, USP (Sterile, Preservative Free) F 004 214
Midazolam 5 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 004 993
Minoxidil 1 mg Oral Capsules Medisca CapsuBlend®-S F 006 747
Misoprostol 100 mcg Oral Capsules Medisca CapsuBlend®-S F 004 851
Morphine Sulfate 1 mg per mL Injection Liquid Sterile Water for Injection, USP F 005 005
Morphine Sulfate 1 mg per mL Epidural Liquid Sodium Chloride 0.9% for Injection, USP (Sterile, Preservative Free) F 003 652
Morphine Sulfate 1 mg per mL Intravenous Liquid Sodium Chloride 0.9% for Injection, USP (Sterile) F 003 623
Morphine Sulfate 1 mg per mL   Epidural Liquid Sodium Chloride 0.9% for Injection, USP (Sterile, Preservative Free) F 003 777
Mycophenolate Mofetil 50 mg per mL Oral Liquid Medisca Oral Suspend F 004 106
Naloxone Hydrochloride 0.4 mg per mL   Injection Liquid Sterile Water for Injection, USP F 005 010
Nitrofurantoin 25 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 931
Nizatidine 15 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 802
Olanzapine 2.5 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 592
Ondansetron Hydrochloride 2.5 mg per mL Injection Liquid Sterile Water for Injection, USP F 004 976
Oseltamivir 12 mg per mL Oral Liquid Medisca Oral Syrup + Medisca Oral Suspend F 001 067
Phenoxybenzamine HCl 2.5 mg Oral Capsules Lactose (Monohydrate), NF F 000 836
Piroxicam 10 mg per mL Oral Liquid Medisca Oral Mix F 007 992
Potassium Chloride 300 mg Oral Capsules Hypromellose (4000 CPS) Methocel E4M, USP + Cellulose (Microcrystalline), NF F 007 899
Pravastatin Sodium 1 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 005 627
Prazosin Hydrochloride 0.5 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 004 637
Prednisolone Phosphate 0.5 Ophthalmic Liquid Purified Water, USP F 001 765
Pregabalin 50 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 007 382
Prochlorperazine Maleate 8.1 mg Oral Rapid-Dissolve Tablets Medi-RDT™ Base F 007 807
Promethazine Hydrochloride 25 mg per mL Intramuscular Liquid Sterile Water for Injection, USP F 004 975
Quetiapine 20 mg Oral Capsules Cellulose (Microcrystalline), NF F 008 015
Rabeprazole Sodium 20 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 472
Ramipril 10 mg per 5 mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup SF F 003 381
Ranitidine 150 mg per 5 mL Oral Liquid Medisca Oral Mix F 006 163
Sildenafil 40 mg Oral Troche  Medisca Troche Base F 006 288
Simvastatin 16 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 536
Sodium Bicarbonate 8.4% Intravenous Liquid Sterile Water for Injection, USP F 001 512
Sodium Chloride 0.9% Injection Liquid Sterile Water for Injection, USP F 002 239
Succimer 250 mg Oral Capsules Medisca CapsuBlend®-S F 008 236
Succinylcholine Chloride 20 mg per mL Intravenous Liquid Sterile Water for Injection, USP F 004 628
Sulfasalazine 50 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 001 689
Tacrolimus 1 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 067
Tamoxifen Citrate 22 mg Oral Capsules Lactose (Monohydrate), NF F 001 025
Terbinafine Hydrochloride 250 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 943
Testosterone 100 mg per mL Intramuscular Liquid Sesame Oil, NF F 004 571
Topiramate 25 mg per 5 mL Oral Liquid Medisca Oral Mix F 006 140
Tramadol Hydrochloride 50 mg Oral Capsules Hypromellose (4000 CPS) Methocel E4M, USP + Cellulose (Microcrystalline), NF F 003 787
Tranexamic Acid 250 mg Oral Capsules Tranexamic Acid, BP F 004 310
Triamcinolone Acetonide 50 mg per mL Injection Liquid Sterile Water for Injection, USP F 003 082
Vancomycin 1 g per 250 mL Intravenous Liquid Sodium Chloride 0.9% for Injection, USP (Sterile) F 003 768
Venlafaxine Hydrochloride 113.15 mg Oral Capsules Lactose (Monohydrate), NF F 001 495
Verapamil Hydrochloride 240 mg per 5 mL G-Tube Liquid Medisca Oral Suspend + Medisca Oral Syrup F 003 499
Warfarin Sodium 1 mg per mL Oral Liquid Medisca Oral Suspend + Medisca Oral Syrup F 002 447

1. The Society of Hospital Pharmacists of Australia. (2017). Medication shortages in Australia. SHPA. Retrieved from: https://www.shpa.org.au/sites/default/files/uploaded-content/website-content/shpa_medicines_shortages_in_australia_report_june_2017.pdf.

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