Sterile
vials 101

Medisca offers a complete range of vial solutions for sterile compounding. With multiple sizes, formats, and packaging configurations available, our portfolio is designed to support flexibility, efficiency, and compliance across sterile workflows.

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Select a size that fits your fill volume and headspace requirements.

5 mL

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30 mL

Understanding vials
in sterile compounding

Vials are the primary container system for many sterile preparations, housing injectables used across hormone therapy, nutraceuticals, animal health, and more. In sterile compounding, vial selection plays an important role in maintaining preparation integrity and supporting aseptic processing from preparation through administration.

Medisca offers two vial formats to support sterile compounding workflows. Ready-to-sterilise (RTS) vials are supplied non-sterile and require in-house sterilisation before use, while ready-to-use (RTU) vials arrive pre-sterilised and are designed for immediate introduction into ISO-classified environments.

Choose the right vial
for your filling process

Select between open and closed vial formats based on your preferred filling process.

Open vials are filled directly before being closed with a rubber stopper and aluminum seal. Available in both RTS and RTU formats, RTS open vials require in-house sterilisation before use, while RTU open vials arrive pre-sterilised, ready for aseptic filling.

Closed vials arrive pre-sterilised on the inside with a stopper and aluminum seal in place. Available in RTU format, these vials are filled by puncturing the stopper with a sterile needle.

What are tubular
and molded vials?

Sterile glass vials are manufactured using two primary methods: tubular and molded. While both are designed to safely contain sterile preparations, each offers different benefits depending on the application.

Tubular vials are made from Type I borosilicate glass tubing. Their uniform glass walls and high clarity make them ideal for sterile filling and freeze-drying (lyophilisation).

Molded vials are made directly from molten glass. Their thicker walls provide added durability for applications where extra strength is needed.

Vials Landing Page What are tubular and molded vials

What is blowback and
why does it matter?

Blowback refers to the shape of the vial neck where the stopper is seated. Vials are available with European blowback, American blowback, or no blowback, each with a distinct neck profile.

The blowback style influences how the stopper fits and is retained on the vial. Selecting the appropriate blowback style and compatible stopper helps support reliable filling, sealing, and overall container closure performance.

Build your
vial system

Start by selecting a non-sterile open vial with the neck design, size, and glass color that best suit your preparation. Blowback and no-blowback neck designs determine the compatible rubber stopper used during filling, while vial size and glass color should be selected based on your formulation, fill volume, and light protection requirements.

Non-sterile open vials

Scalable filling solutions
with EZ-fill® RTU vials

Through our partnership with Stevanato Group, Medisca offers EZ-fill® ready-to-use (RTU) vials to simplify aseptic filling. Supplied pre-washed, depyrogenated, and sterilised, EZ-fill® vials arrive ready to use, reducing preparation and saving time.

Available in Nest & Tub and Tray configurations, they support everything from manual filling to automated production. Compatible with more than 30 fill-and-finish systems, EZ-fill® vials make it easy to scale your operation as your needs grow.

Learn about EZ-fill vials