MAZ® Mixer – FAQs

Training and onboarding

How will the initial training be provided?

Customers will have access to onboarding videos for self-instruction/learning. Additionally, live virtual onboarding sessions will be available for customers who prefer interactive training.

Technical Support

What are the available support options?

The MAZ team provides technical support and assistance for any support-related questions or concerns, Monday through Friday, during normal business hours.

What additional support can I expect to receive as a MAZ customer?

  • On-boarding options: Live sessions or self-instruction
  • Technical support via the MAZ portal
  • Access to the dedicated MAZ lab for continued research and development

Can I visit the MAZ lab in Arizona to see the different MAZ units?

Yes! Please contact a member of our MAZ team, and we'll be happy to arrange your visit. Our demonstrations cover the various units, offer troubleshooting assistance, and provide hands-on training.

Maintenance

What additional maintenance is required for the MAZ mixer? How do I clean it?

The MAZ mixer  requires minimal to no maintenance:

  • For KK-300: Change the white belt
  • For KK-400/1000: Grease gears every 50 hours or every three months

How can I prevent leakage in regular MAZ jars when mixing suspensions, especially to avoid sticky residue?

A good rule of thumb is not to fill the jars more than 80% full. Check the fill level to ensure it doesn't exceed the recommended maximum, and use seals and lids properly.

Product features & comparison

How does the MAZ mixer differ from an unguator or electronic mortar & pestle?

The MAZ mixer does not require mixing rods or blades, which reduces the risk of cross-contamination and eliminates the incorporation of air or microplastics within the compound.

How does the MAZ mixer eliminate the need for an ointment mill?

  • By utilizing zirconia beads and a stainless-steel liner inside the MAZ mixer, we break down particle sizes of powders and tablets efficiently
  • We can levigate and solubilize powders into wetting agents or bases, reducing the grittiness of creams and ointments
  • Through high shearing force, the MAZ technology homogenizes and deaerates compounds, resulting in pharmaceutically elegant finished products

How does the MAZ mixer distinguish itself from other planetary mixers?

  • Over 10 years of ongoing research and development
    • 8+ patents
    • 175+ formulas
    • Proprietary operating procedures
    • adapter mixing capablilities
  • Access to the dedicated MAZ lab and MAZ specialists at no additional cost

How can the MAZ technology help me grow my practice?

The MAZ mixer is a groundbreaking technology that seamlessly integrates into your compounding lab's workflow. You can leverage the quality and consistency of compounds produced by the MAZ technology to engage with prescribers and attract new business. Additionally, showcasing the use of the MAZ mixer in your pharmacy on social media or other marketing platforms can highlight your commitment to delivering the highest quality care to your patients.

 What options are available if my MAZ mixer can't keep up with the growing volume in my pharmacy?

At Medisca, we're committed to evolving alongside your business. We offer a trade-in program that allows you to upgrade to a machine that meets your expanding compounding lab's needs.

Can the MAZ mixer help improve my turnaround time and delivery with the recent growth in my pharmacy?

Absolutely! The MAZ technology significantly reduces mixing, transferring, and cleanup times, streamlining your workflow for faster turnaround times. This enhancement ensures you can provide timely service to your patients, elevating their overall customer experience.

Can the MAZ mixer address the increased volume challenge faced by my pharmacy when using an unguator?

Absolutely! The MAZ technology uses planetary motion that employs a mixing technique that thoroughly homogenizes your preparation while eliminating air entrapment. This results in a superior finished product and ensures accurate dosing for your patients.

Can I still use a Beyond-Use Date (BUD) if the mixing procedure has changed from the current process to the MAZ mixer process?

To maintain an extended BUD based on a stability study, the formula's ingredients and their quantities must remain unchanged. This means that the client must compound the formula with the exact ingredients and quantities used for the stability study. Presently, the USP does not specify a particular technology or mixing method that must be followed.

What additional accessories are available for the MAZ mixer?

  • Mixing containers:
    • Standard mixing containers: 300mL, 400mL, 1.1L
    • Standard mixing container for adapter insert
    • Disposable mixing liners
  • Milling accessories:
    • Stainless steel mixing liners
    • Zirconia milling beads
  • Mixing adapters:
    • MD Pump mixing adapter
    • Jar mixing adapters
    • KK-250S and KK-300SS standard container adapter set
    • Samix jar mixing adapter

How does the MAZ mixer eliminate the need for a RAM Mixer, V-Blender, or Powder Mixer?

  • By harnessing the gravitational forces generated by MAZ technology, it becomes possible to efficiently blend various types of powders for encapsulation within just a few minutes.
  • The MAZ mixer can complete 1:10000 powder dilutions in a matter of minutes
  • The MAZ mixer, with its simultaneous homogenization and deaeration capabilities, enables the effective removal of static from progesterone capsule mixtures. This enhancement not only accelerates the encapsulation process but also minimizes loss, making it more efficient.

Financial options

What is the cost of the MAZ mixer?

We offer various model sizes and functionalities, so the price is best determined based on individual needs. To get more information, request a demo.

What payment options are available for the MAZ mixer?

Customers may qualify for financing at 0% interest with a down payment, subject to approval on a case-by-case basis. For more details and to explore financing options, it's recommended to consult with a MAZ Application Specialist. For more information, request a demo.

How does the MAZ mixer maximize return on investment (ROI)?

  • Cost savings: The MAZ technology significantly reduces both labor and consumable costs
  • Time efficiency: It cuts down mixing times and cleanup efforts by homogenizing and deaerating directly in dispensing devices like MD Pumps, UnoDose, and various sizes of suspension bottles
  • Increased output: With reduced compound times, the MAZ mixer enables customers to scale up their compounding output while maintaining quality and timely service for their patients
  • Versatility: The MAZ mixer covers a wide range of preparations, including creams, ointments, suspensions, troches, suppositories, capsules, and veterinary medications, all within a single machine

Product usage & applications

Does it make sense for me to use the MAZ technology if I only compound topical preparations?

Absolutely! The MAZ technology enables you to prepare topical compounds more efficiently, setting your pharmacy apart in terms of quality compared to competitors in your area. Additionally, the versatility allows you to expand your patient offerings beyond topicals. When you receive prescriptions for other dosage forms like capsules, suspensions, troches, suppositories, or veterinary treats, the MAZ mixer ensures you can deliver these preparations promptly to your patients.

Can Benzocaine/Lidocaine/Tetracaine (BLT) be compounded in the MAZ mixer?

Absolutely. BLT is recognized as a challenging and time-consuming compound to produce. The MAZ technology streamlines the compounding process, reducing both time and the need for an ointment mill. This not only saves time but also minimizes mess and product loss during preparation.

Can you compound Lidocaine 23%/Tetracaine 7% in the MAZ mixer?

Yes! We have developed specific mixing methods in the MAZ mixer to produce a smooth, homogeneous ointment without the need for an ointment mill.

Cannabis

What is NanoSil made from?

NanoSil is a micro granular amorphous Crystal with positively charged nano-sized pores. It is designed as a superior inert carrier for pharmaceutical applications. NanoSil has a unique internal structure and remarkable flow properties, providing high internal porosity and superior compressibility properties.

Is it safe to smoke or inhale NanoSil powder?

No, NanoSil is not recommended for smoking or inhalation purposes.

What are the benefits of turning your active ingredient into powder form?

  • Reduced reactivity with cannabis extract and actives
  • High porosity with excellent oil adsorption capacity (up to 3.3ml/g) and solid dispersion capabilities
  • Enhanced tableting ability due to unique structure and processing, improving flowability and compressibility
  • Compliant with pharmaceutical regulations
  • Increased bioavailability
  • Provides moisture protection
  • Acts as a taste masker by reducing surface area, absorbing actives, and masking 80-90% of taste
  • Facilitates easier handling of the material

Do you require a state license to use the MAZ mixer for cannabis?

No, the MAZ mixer is specifically designed to enhance efficiency in the production and manufacturing of finished products without necessitating a state license.

Can you directly infuse cannabis flowers using the MAZ mixer?

Absolutely. The MAZ mixer is equipped with special adapters and settings that are ideal for flower infusion.

Can vapes be made using the MAZ mixer?

Absolutely. It's excellent for homogenizing distillate with botanical or cannabis-derived terpenes.

Oral Medications

What is the Medisca MAZ® mixer and how is it used in oral preparations?

The Medisca MAZ® mixer is an all-in-one planetary mixing device used in pharmaceutical compounding. In Australia, it’s widely adopted in pharmacies to efficiently compound oral medications such as suspensions, capsules, powders, troches, and oral gels. The MAZ® mixer performs mixing, milling, melting, and deaeration in one closed system, helping compounders achieve homogenous, dose-accurate oral medications quickly and safely.

Can the MAZ® mixer be used to make oral suspensions and liquids?

Yes. The MAZ® mixer is ideal for preparing oral suspensions and liquids. It ensures a smooth, uniform texture by evenly dispersing active pharmaceutical ingredients (APIs) into suspension bases. This improves patient compliance, especially in paediatrics, aged care, and veterinary settings. It also supports commonly used Australian compounding bases.

How does the MAZ® mixer help with oral capsule compounding in Australia?

For oral capsules, especially static-prone powders like progesterone or testosterone, the MAZ® mixer enables fast and uniform blending using compatible tools like Medisca’s CapsuBlend®. This minimises segregation, reduces static issues, and ensures consistent dosing—essential for regulatory compliance and patient safety in Australia.

Is the MAZ® mixer compatible with oral troches and lozenges?

Absolutely. The MAZ® mixer can melt and mix APIs directly into troche or lozenge bases without using open beakers or hot plates. This reduces manual handling and improves safety, particularly when compounding hormone troches for personalised therapies.

What are the benefits of using the MAZ® mixer for oral compounding in Australian pharmacies?

Key benefits include: 

  • Faster mixing and preparation times
  • Consistent dosing and homogeneity
  • Reduced product loss and cross-contamination
  • Compliance with USP 800-style handling for hazardous drugs
  • Compatibility with oral dosage forms like liquids, capsules, troches, and more 

These features make it a valuable tool for improving workflow and product quality in Australian compounding pharmacies. 

Does the MAZ® mixer support USP 800 compliance in Australia?

While USP 800 is a U.S. standard, many Australian pharmacies follow similar best practices for handling hazardous medications. The MAZ® mixer’s closed system minimises airborne exposure and reduces the risk of cross-contamination, aligning with USP 800-style safety protocols and helping compounders meet Australian workplace health and safety standards.

What types of oral medications can I prepare with the MAZ® mixer?

With the MAZ® mixer, you can prepare: 

  • Oral suspensions 

  • Solutions 

  • Capsules 

  • Powders 

  • Troches 

  • Lozenges 

  • Oral gels and pastes 

It supports a wide range of therapeutic areas including hormone therapy, paediatrics, veterinary, geriatric, and custom formulations. 

Is training available for Australian pharmacies using the MAZ® mixer?

Yes. Medisca provides training, support, and access to a growing library of validated formulas designed specifically for use with the MAZ® mixer. Australian pharmacies can also request product demos and access educational resources through Medisca Australia.

Topical Treatments

What is the Medisca MAZ® mixer?

The Medisca MAZ® mixer is an advanced compounding device that uses bead milling and high-shear mixing to produce smooth, uniform formulations. It’s designed to work with a wide range of bases—creams, gels, suspensions, ointments, and powders—and is ideal for both pharmaceutical and cosmetic applications.

How does the MAZ mixer improve topical formulations?

The MAZ mixer significantly reduces particle size, leading to smoother textures and better absorption. It also improves the distribution of active ingredients and minimizes oxidation, resulting in more stable and professional-grade topical dermatological and hormonal products.

What types of formulations is the MAZ mixer best suited for?

The MAZ mixer is ideal for: 

  • Dermatological creams and gels 

  • High-powder formulations (e.g., spironolactone, tretinoin, azelaic acid) 

  • Cosmetic bases with sensitive actives like kojic acid or ascorbic acid 

  • Hormone creams 

  • Suspensions and liquids prone to clumping or sedimentation 

How does the MAZ mixer work?

The MAZ mixer uses stainless steel liners, zirconia milling beads, and a rotating motion to create shear and reduce particle size. Its built-in deaeration feature removes trapped air, preventing bubbles and oxidation. 

Formulas can be mixed directly in the final dispensing container using accessories like the MAZ bottle adapter, minimizing product loss and cleanup time. 

Who should use the MAZ mixer?

The MAZ mixer is designed for: 

  • Compounding pharmacies 

  • Cosmetic chemists and formulation labs 

  • Dermatologists offering in-house compounded skincare 

  • Research labs working with custom topicals 

  • Clinics preparing small-batch skin treatments or hormone therapies 

How does the MAZ mixer compare to traditional methods like ointment mills or unguators?

 

Feature MAZ Mixer Ointment Mill Unguator 
Particle size reduction Excellent Good Fair 
Homogenization High shear + bead milling Manual dispersion Emulsifying paddle 
Oxidation control Deaeration built-in None None 
Clean-up Minimal (in-container mixing) High Medium 
Best for Complex or powder-heavy formulas Simple creams Light emulsions 

 

Can the MAZ mixer handle active ingredients like tretinoin, kojic acid, or hydroquinone?

Yes. The MAZ mixer is highly effective for hard-to-process actives like: 

  • Tretinoin 

  • Kojic acid 

  • Hydroquinone 

  • Spironolactone 

  • Ascorbic acid 

  • Niacinamide 

Its bead milling technology ensures fine dispersion and reduces the risk of graininess or instability. 

Is the MAZ mixer available in Australia?

Yes. Medisca offers full support, distribution, and training for the MAZ mixer across Australia. Orders can be shipped nationwide, and local demonstrations or virtual training sessions are available.

What accessories are compatible with the MAZ mixer?

 

  • MAZ Bottle Adapter – Enables mixing directly in common containers like MD Pumps, Samix jars, and dual-neck bottles. 

  • Stainless Steel Liner – Durable and easy to clean. 

  • Zirconia Milling Beads – For particle size reduction and smoothing. 

  • Cleaning Kit – Ensures hygiene and compliance with GMP/TGA standards. 

How do I clean the MAZ mixer?

The MAZ mixer is designed for quick cleaning. Most compounds can be wiped or rinsed from the stainless steel liner. For full sanitation: 

  1. Remove the liner and beads 

  2. Use approved cleaning agents 
  3. Rinse and dry thoroughly 
  4. Autoclave (optional, if required) 

Cleaning protocols follow USP <795> and <800> guidelines where applicable. 

Where can I buy or request a demo of the MAZ mixer?

You can purchase the MAZ mixer directly from Medisca Australia or contact the local sales team for a demo. Virtual training and formulation support are also available. 

What do pharmacists and formulators say about the MAZ mixer?

Australian pharmacists report: 

  • Faster compounding times 

  • More elegant, stable formulations 

  • Easier cleanup and less product waste 

  • Improved consistency in hormone and dermatology creams 

“We switched to the MAZ mixer for our tretinoin and hydroquinone creams. The texture and color are far superior—and cleanup takes half the time.” — Compounding Pharmacist, Melbourne 

Want to Learn More?

Explore formulation guides, demo videos, and real-world case studies on Medisca.com.au.

Sterile Compounding

Can the Medisca MAZ® mixer be used for sterile compounding in Australia?

Yes. The Medisca MAZ® mixer is suitable for sterile compounding processes in Australia, particularly within hospital, clinical, and specialty pharmacy settings. It supports closed-system mixing of sterile preparations in ISO Class 5 environments, improving efficiency, consistency, and operator safety while helping meet regulatory and sterility standards.

What sterile dosage forms can be prepared using the MAZ® mixer?

The MAZ® mixer supports the preparation of a wide range of sterile compounded medications, including: 

  • Intravenous (IV) solutions 

  • Intramuscular (IM) and subcutaneous (SC) injections 

  • Ophthalmic solutions and suspensions 

  • Intrathecal injections 

  • Irrigation solutions 

  • Inhalation solutions (nebulisable) 

  • Sterile suspensions and emulsions 

Its planetary mixing and deaeration capabilities are ideal for compounding sensitive sterile formulations where uniformity and particulate control are critical. 

How does the MAZ® mixer support sterile compounding best practices in Australia?

The MAZ® mixer enables mixing, milling, melting, and deaeration within a sealed container, significantly reducing exposure to contaminants and maintaining the integrity of sterile ingredients. When used in a cleanroom or laminar flow hood (ISO Class 5 or better), the system supports PIC/S Guide to GMP and TGO No. 101 standards relevant to sterile compounding in Australia.

What are the benefits of the MAZ® mixer in sterile ophthalmic compounding?

Ophthalmic medications require extreme precision, clarity, and sterility. The MAZ® mixer can: 

  • Disperse APIs evenly in sterile aqueous or oil-based ophthalmic vehicles 

  • Reduce particulate matter with integrated milling media 

  • Remove entrapped air to prevent microbubble formation 

  • Ensure uniformity and homogeneity critical for ocular safety 

This makes it ideal for Australian compounders preparing sterile eye drops, ointments, and gels

How does the MAZ® mixer help reduce contamination risk in sterile compounding?

The MAZ® mixer operates as a closed system, eliminating the need for open beakers, stir bars, or transfer containers. This reduces the number of manual steps and surface contact points, which are common sources of contamination. Fewer transfers also mean less product loss and greater sterility assurance.

Can the MAZ® mixer be used for hazardous sterile compounding (e.g., chemotherapy)?

Yes. For hazardous sterile compounding, such as cytotoxic or chemotherapy preparations, the MAZ® mixer helps contain exposure within a sealed container and can be operated inside a biological safety cabinet (BSC). This supports USP <800>-style practices and aligns with Australian WHS guidelines for compounding hazardous sterile medications.

Does the MAZ® mixer improve quality and consistency in sterile injectable preparations?

Absolutely. The MAZ® mixer provides: 

  • Homogenous blending of actives and excipients 

  • Particle size reduction for suspensions and emulsions 

  • Deaeration to prevent air entrapment and bubble formation 

  • Repeatable, validated mixing parameters 

This is essential for ensuring dose accuracy, stability, and patient safety, particularly for injectables prepared in hospital pharmacy settings across Australia. 

Is the MAZ® mixer compatible with sterile single-use containers?

Yes. The MAZ® system is compatible with a range of sterile, single-use containers and can be adapted to work with specific sterile packaging formats. This supports cleanroom efficiency and aligns with contamination control protocols in Australian facilities.

What role does the MAZ® mixer play in hospital-based sterile compounding?

In Australian hospitals, the MAZ® mixer: 

  • Streamlines sterile batch preparation for high-demand injectables 

  • Reduces manual handling of cytotoxics and biologics 

  • Improves turnaround time in aseptic compounding units 

  • Ensures repeatable, validated outcomes for TGA-registered and extemporaneous formulations 

It is especially beneficial for on-demand sterile compounding, reducing reliance on external suppliers. 

Does Medisca offer sterile compounding support for Australian pharmacies?

Yes. Medisca Australia provides technical support, validated formulations, SOPs, and ongoing training for pharmacies using the MAZ® mixer in sterile environments. They also assist with cleanroom integration, regulatory guidance, and equipment calibration to ensure consistent and compliant use of the system.